Medicinal Chemistry Network | Drug Discovery, Therapeutic Challenges, Chemistry

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Targeting the Bromome: are we there yet?

By MedChemNet on Sep 27, 2016

This free article, brought to MedChemNet users by our sister journal Future Medicinal Chemistry, discusses the potential of bromodomains as drug targets.

Antimicrobial drug discovery: the teixobactin story

By Kim Lewis on Sep 23, 2016

As part of MedChemNet’s focus on antimicrobial drug discovery, I discuss my team’s work discovering the novel antibiotic teixobactin.

Catalyst washing...... Can any one tell me about which solvent is use for washing the MnO2 catalyst for reusing purpose.... Reference....... If possible....!!!!

See DOI: 10.1039/C5NJ03140K doi:10.1016/j.tetlet.2012.03.091 `

By Ramaswamy Narayanan on Jun 05, 2016

What free docking programme would you recommend?

RMSD issue...

`As site editor for MedChemNet, I'm pleased to provide this response from networker Dr Harish Kundaikar: "The idea of simulation for 10ns seems to be just enough as this is the statistically sign... Read more » `

By Stella Bennett on May 31, 2016

Is there any article on effect of attachment of Omega Fatty acid to the active compound/molecule(s)/drug(s) for the betterment of drug metabolism.

`You may want to take a look at the following references: PMCID: PMC3537895 doi:10.1016/j.molbiopara.2015.03.004 The question needed to be better defined. Then a simple Google query will give you... Read more » `

By Ramaswamy Narayanan on Jun 05, 2016