Natural Product Drug Discovery Revival?
Are we witnessing a turning point associated with revival of natural products as a drug discovery source?
After decades of decreased interest in natural product drug discovery by the pharmaceutical industry, the 2015 Nobel Prize in Physiology or Medicine was given to scientists who profoundly contributed to the successful pharmaceutical development of two natural products, Avermectin and Artemisinin. Recent publication trend analysis also indicates a sharp increase of the scientific interest in the research area of natural product drug discovery (http://dx.doi.org/10.1016/j.biotechadv.2015.08.001). On the background of these observations, it is very exciting to follow future developments that will show whether we are witnessing a turning point associated with re-evaluation of the value of natural molecules as a drug discovery source.