Content matching 'protein protein interactions'
A team led by Stony Brook University (NY, USA) researchers has developed a new method to model protein–protein interactions, research that may help to accelerate future drug discovery.
Single amino-acid substitution could turn banana protein into viable new antiviral
Open access data on the behaviors of druggable proteins is expected to aid cancer translational research
New data made available through publicly accessible database canSAR is anticipated to help support target validation in drug discovery
A deeper understanding of the host factor's function may lead to promising new ways to target HIV
Researchers from Carnegie Mellon University (PA, USA) have created the first robotics-driven system to determine the effects of drugs on proteins, drastically reducing the number of necessary experiments.
New understanding of crucial molecular enzyme could lead to Alzheimer’s and cancer therapies.
We highlight the possibility of developing an alternative approach to signal transduction therapy, in which the drugs would be used to generate unnatural cell signaling pathways rather than (or in addition to) affecting the existing ones
Where do the new opportunities lie?
Researchers from the University of Pennsylvania (Philadelphia, PA, USA) and Fox Chase Chemical Diversity Center (Doylestown, PA, USA) have found a novel kind of chemical compound that could potentially be used to treat Ebola virus infection.
New class of spiral polypeptide targets bacterial outer membrane
A research team from Cold Spring Harbor Laboratory (NY, USA) and Boehringer Ingelheim (Ingelheim am Rhein, Germany) has demonstrated a new, highly accurate method of proving how certain drugs work.
A team from The Scripps Research Institute (La Jolla, CA, USA) has identified a novel anti-obesity, anti-diabetes drug target.
In this interview, we speak to Future Medicinal Chemistry Editorial Board Member Giovanna Zinzalla about her work at the interface of chemistry and biology, her female scientific role models and the importance of strong support network in encouraging women in science.
Our network journals are sharing exclusive free content with MedChemNet members
Free to access editorial by Rebecca A Kaner and Peter Scott from Volume 7, Number 1 of Future Medicinal Chemistry
We speak to Professor Sir Tom Blundell about his former colleague, Nobel Laureate Dorothy Hodgkin
Transcription factors and epigenetic mechanisms of action: insights and perspectives from NMCS 2016
Study of breast cancer cells suggests new approaches to drug discovery and cancer treatment.
Since the chemical diversity of vendor-supplied libraries is not always relevant to biological function, an earnest plea is being made to the chemical library vendors to advance the chemical methodology and library development technology platform to increase the natural product-like attributes and thus play their part in improving the success of our lead finding efforts.